Ear psoriasis is quite common among those suffering with psoriasis and occurs in approximately 18 percent of all psoriasis sufferers. Dry scales or scaly patches in the ear canal are often diagnosed as a form of psoriasis. Psoriasis in the ears may result buildup of scales that blocks the ear canal. This scaling can cause a blockage of the external ear canal resulting in temporary hearing loss. Ear psoriasis is normally limited to the area of the external surface of the ear canal, and is usually not seen inside the ear itself or behind the eardrum. Ear psoriasis may also occur behind the ear. The symptoms of ear psoriasis include dryness of the skin in the ear, with some scaling.
Treatment of ear psoriasis may include gentle cleansing of the ear area, which can be accomplished using basic over-the-counter ear-cleaning kits. Plain warm water, followed by a thin layer of mineral or jojoba oil which is applied with a cotton swab to the outer area of the ear brings relief to many psoriasis sufferers. Wearing wax earplugs when sleeping has been effective for some in keeping the affected ear canal from drying out and thus reducing the severity of ear psoriasis. Another solution is to apply Psoriasis-Ltd to the outer surface of the ear. This product has been found to improve the appearance of scales, redness and irritation resulting from psoriasis of the ear.
Friday, January 27, 2012
Thursday, October 06, 2011
Cause of Psoriasis
Skin researchers believe that a biochemical malfunction results in rapid skin growth production causing psoriasis. Heredity may also be a factor.
Research has found that psoriasis may the result of an immune system malfunction causing inflammation of the skin and increased cellular production and turnover. Normal cellular function completes its cycle every 30 days. But in psoriasis the skin goes through this whole process in 3-6 days.
Research has found that psoriasis may the result of an immune system malfunction causing inflammation of the skin and increased cellular production and turnover. Normal cellular function completes its cycle every 30 days. But in psoriasis the skin goes through this whole process in 3-6 days.
Wednesday, January 26, 2011
Psoriasis Treatment
Treatment options for psoriasis have come a long way. Psoriasis treatment is based on the sufferer’s age, the severity of their condition, and the type of psoriasis they have. Psoriasis tends to flare-up when the person is exposed to certain trigger factors. Substances or conditions that can worsen psoriasis include changes in climate, infections, stress, and dry skin. Also, certain medicines may cause an outbreak or worsening of the disease. A natural treatment to improve psoriasis can be found in basic lifestyle changes.
Research indicates that ocular symptoms of psoriasis occur in approximately 10% of psoriasis sufferers. Ocular psoriasis can cause symptoms including inflammation of the eye, dryness and discomfort. When psoriasis affects the eyelids, scales may cover lashes. The edges of the eyelids may become red and crusty. If inflamed for long periods, the rims of the lids may turn up or down. If the rim turns down, lashes can rub against the eyeball and cause irritation. In a prolonged ocular episode vision impairment may occur. Ocular psoriasis treatment is aimed at preventing irritation and controlling inflammation.
Many people have found that Psoriasis-Ltd is the the answer.Patients have seen an excellent improvement in the appearance of their psoriasis after starting the application of Psoriasis-Ltd. Psoriasis-Ltd does not stain clothes or bedding, does not smell, and dries invisibly on the skin in less than 20 seconds
Research indicates that ocular symptoms of psoriasis occur in approximately 10% of psoriasis sufferers. Ocular psoriasis can cause symptoms including inflammation of the eye, dryness and discomfort. When psoriasis affects the eyelids, scales may cover lashes. The edges of the eyelids may become red and crusty. If inflamed for long periods, the rims of the lids may turn up or down. If the rim turns down, lashes can rub against the eyeball and cause irritation. In a prolonged ocular episode vision impairment may occur. Ocular psoriasis treatment is aimed at preventing irritation and controlling inflammation.
Many people have found that Psoriasis-Ltd is the the answer.Patients have seen an excellent improvement in the appearance of their psoriasis after starting the application of Psoriasis-Ltd. Psoriasis-Ltd does not stain clothes or bedding, does not smell, and dries invisibly on the skin in less than 20 seconds
Monday, January 17, 2011
The Cause of Psoriasis
The key to sucessfully treating psoriasis is understanding the cause of psoriasis. It is believed that a biochemical stimulus triggers a faster skin growth. The body can't keep up with this accelerated rate of growth and as a result patches of raised skin accumulate.
Research shows that heredity also plays a role in the development of psoriasis. Individuals who have a family member with a severe case of psoriasis tend to experience early onset of symptoms of the disease.
Recent research studies indicate that a disorder within the immune system may also contribute to psoriasis. The T cell, a white blood cell, normally works to fight off infection and disease. Scientists believe that having an abnormal immune system can cause abnormal activity by T cells in the skin. These abnormally active T cells cause skin inflammation and increased cell production.
Diet and vitamin influences have also been thought to play a role in the cause of the development and progression if this condition.
Research shows that heredity also plays a role in the development of psoriasis. Individuals who have a family member with a severe case of psoriasis tend to experience early onset of symptoms of the disease.
Recent research studies indicate that a disorder within the immune system may also contribute to psoriasis. The T cell, a white blood cell, normally works to fight off infection and disease. Scientists believe that having an abnormal immune system can cause abnormal activity by T cells in the skin. These abnormally active T cells cause skin inflammation and increased cell production.
Diet and vitamin influences have also been thought to play a role in the cause of the development and progression if this condition.
Thursday, October 14, 2010
The Psoriasis-Ltd Glossary of Psoriasis Terms
Understanding the terminology used to define, diagnose and treat psoriasis helps you to communicate effectively and fully understand your psoriasis treatment and medication options. This glossary defines commonly used psoriasis terms, including names of products and medications used in the treatment of psoriasis and skin related conditions that may co-exist with psoriasis, such as acne, eczema, lupus, and rosacea.
Thursday, June 24, 2010
Psoriasis Can Occur of The Scalp
The symptoms of seborrheic scalp psoriasis usually consists of red, scaly patches that may appear lumpy. The edges of these patches tend to be well defined. Psoriasis on the scalp is common and, in many cases, it is the only area affected. Seborrheic scalp psoriasis can extend beyond the hairline, onto the forehead. Psoriasis of the scalp does not damage the hair follicle and is not associated with hair loss, but if the scale is thick and forms hard lumps, it may lead to temporary hair thinning. The scalp may be the first site on the body to be affected by psoriasis.
Treatment for scalp psoriasis should include massaging a little warm baby/olive/coconut oil gently into the scalp, (wrap the head in an old towel). Wash out with cream shampoo (i.e. Dry Hair Products) and add a little lemon juice to the final rinse to get rid of excess grease. Only shampoo three times a week, more than this and the natural oils may be washed out. daily treatemnt for scalp psoriasis may include a once to twice application of Psoriasis Ltd. To apply Psoriasis Ltd, dampen the fingers with water, and wet the affected area of the scalp with the finger. Then apply the Psoriasis Ltd disk by gliding it over the affected area to dissolve a small amount onto the area using a circular motion with only one small application of about 2-4 seconds.
Treatment for scalp psoriasis should include massaging a little warm baby/olive/coconut oil gently into the scalp, (wrap the head in an old towel). Wash out with cream shampoo (i.e. Dry Hair Products) and add a little lemon juice to the final rinse to get rid of excess grease. Only shampoo three times a week, more than this and the natural oils may be washed out. daily treatemnt for scalp psoriasis may include a once to twice application of Psoriasis Ltd. To apply Psoriasis Ltd, dampen the fingers with water, and wet the affected area of the scalp with the finger. Then apply the Psoriasis Ltd disk by gliding it over the affected area to dissolve a small amount onto the area using a circular motion with only one small application of about 2-4 seconds.
Tuesday, June 15, 2010
Natural Treatment of Psoriasis
It is important to approach the treatment of psoriasis in as many ways as possible. Those whose treatment choices include modifying their lifestyles, eating habits and reduce their level of stress often experience a much greater degree of psoriasis clearing. While you try to treat the symptoms of psoriasis that are most visible and distressing, you should attempt to address the treatment of the cause! If we find and treat the cause of psoriasis, then maybe all the symptoms of psoriasis need not occur!
Natural treatment tips:
1) Keep the body well hydrated with alkaline water.
2) Moisturize, moisturize, moisturize.
3) Avoid skin irritants.
4) Launder clothing with mild soap or detergent.
5) Keep nails clean and short to prevent scratching.
6) Avoid temperature and humidity extremes.
7) Stress can trigger a psoriasis flares.
8) Many medications can also affect psoriasis.
Learn more about psoriasis at Psoriasis-Ltd.
Natural treatment tips:
1) Keep the body well hydrated with alkaline water.
2) Moisturize, moisturize, moisturize.
3) Avoid skin irritants.
4) Launder clothing with mild soap or detergent.
5) Keep nails clean and short to prevent scratching.
6) Avoid temperature and humidity extremes.
7) Stress can trigger a psoriasis flares.
8) Many medications can also affect psoriasis.
Learn more about psoriasis at Psoriasis-Ltd.
Thursday, March 04, 2010
Psoriasis Can Occur In The Ear Canal
Psoriasis may be present as dry, flaky pacthes within the ear canal. Ear psoriasis can cause scales to accumulate creating a blockage the ear canal. Ear Psoriasis is usually located on the outside ear canal or behind the ear itself. Dryness of the skin in the ear, with some scaling is characteristic of psoriasis. Psoriasis of the ears occurs in approximately 18 percent of all patients at some time.
Tuesday, November 17, 2009
KOEBNER’S PHENOMENON PSORIASIS
The “Koebner phenomenon” was named after Dr. Koebner who in the 19th century observed that a patient developed new psoriasis lesions in areas where his horse bit him. One may observe a new psoriasis flare within 10 to 14 days following an injury to the skin. A Koebner phenomenon has been observed in approximately half of all psoriasis patients, but may also occur with eczema, or dermatitis. In some cases shaving or even the adhesive from a band aid can result in Koebner’s phenomenon.
Thursday, October 29, 2009
Defining Psoriasis
Psoriasis is a non-contagious disorder which affects the skin. As a result, symptoms including itchy, scaly red patches appear, often on the elbows, hands, feet, and scalp, but they can show up on other parts of your body. Usually, what happens is new skin cells take about a month or so to move from the deepest skin layer where they're produced, to the surface where they die and flake off. With psoriasis, the entire skin cell life cycle takes only days.
Individuals with psoriasis experience skin conditions such as itching, cracking, stinging, burning, or bleeding. These symptoms are usually worse in the winter months due to the lack of sunlight and low indoor humidity. The skin is most likely to crack at the joints where the body bends or in areas where the individual fails to refrain from scratching. Scratching can also lead to bleeding and infection, which is why it should be avoided at all costs. This skin condition has also been known to affect fingernails and toe nails by causing pits or dents in them. There is also the possibility that the soft tissue inside the mouth and genitalia can be affected. In some cases, individuals experience joint inflammation, which can lead to the development of arthritis symptoms. This condition is known as psoriatic arthritis.
There are many beliefs as to what causes psoriasis. Although no one knows for sure, many scientists believe that a biochemical stimulus triggers the abnormally high skin growth, which in turn causes the symptoms of skin lesions. Heredity also plays a role in the development of psoriasis symptoms. Individuals who have a family member with a severe case of psoriasis tend to experience early onset of the disease. Recent research studies indicate that psoriasis may be a disorder of the immune system. The T cell, a white blood cell, normally works to fight off infection and disease. Scientists believe that having an abnormal immune system causes abnormal activity by T cells in the skin. These abnormally active T cells cause skin inflammation and increased cell production. Diet and vitamin influences have also been thought to play a role in psoriasis development and progression.
Individuals with psoriasis experience skin conditions such as itching, cracking, stinging, burning, or bleeding. These symptoms are usually worse in the winter months due to the lack of sunlight and low indoor humidity. The skin is most likely to crack at the joints where the body bends or in areas where the individual fails to refrain from scratching. Scratching can also lead to bleeding and infection, which is why it should be avoided at all costs. This skin condition has also been known to affect fingernails and toe nails by causing pits or dents in them. There is also the possibility that the soft tissue inside the mouth and genitalia can be affected. In some cases, individuals experience joint inflammation, which can lead to the development of arthritis symptoms. This condition is known as psoriatic arthritis.
There are many beliefs as to what causes psoriasis. Although no one knows for sure, many scientists believe that a biochemical stimulus triggers the abnormally high skin growth, which in turn causes the symptoms of skin lesions. Heredity also plays a role in the development of psoriasis symptoms. Individuals who have a family member with a severe case of psoriasis tend to experience early onset of the disease. Recent research studies indicate that psoriasis may be a disorder of the immune system. The T cell, a white blood cell, normally works to fight off infection and disease. Scientists believe that having an abnormal immune system causes abnormal activity by T cells in the skin. These abnormally active T cells cause skin inflammation and increased cell production. Diet and vitamin influences have also been thought to play a role in psoriasis development and progression.
Thursday, January 04, 2007
Understanding Psoriasis
Psoriasis is a chronic scaling skin. It may range from just a few spots anywhere on the body to large areas of involvement. It is not contagious or spread able from one part of the body to another or from one person to another. There is no blood test to diagnose psoriasis. The diagnosis is made by observation and examination of the skin. Sometimes microscopic examination of the skin (biopsy) is helpful where the changes are not typical or characteristic. The exact cause of psoriasis is unknown, but hereditary and genetic factors are important. Psoriasis runs in families. This does not mean, however, that every child of a parent with psoriasis will develop psoriasis, but it is common that somewhere down the line psoriasis will appear in families. Psoriasis is not caused by allergies, infections, dietary deficiencies or excesses, or nervous tension.
Monday, December 04, 2006
Molecule Against Psoriasis
A number of chronic diseases break out because the body attacks an imaginary enemy. A research group at the Norwegian University of Science and Technology (NTNU) has created a molecule that prevents our immune system from running wild.
When the body thinks it is under attack, it defends itself in the best way possible, for instance by starting a defence inflammation.
This reaction is highly appropriate if the enemy is an influenza virus or something else that actually needs to be fought. However, sometimes the body misinterprets the signals, and starts a defence inflammation against a non-existent enemy. The result could be so-called autoimmune diseases: psoriasis, arthritis, Bechterew’s, asthma, allergies, ulcerative colitis, multiple sclerosis, Crohn’s disease – and numerous others. The list is longer than we care to imagine, and affects large parts of the population. “Judas enzyme” sends the wrong messageProfessor Berit Johansen at the Department of Biology at NTNU previously discovered which enzyme that misinterprets signals and reprograms cells to divide much faster than they should – thus provoking disease. The enzyme is called phospholipase A2, less formally known as the “Judas enzyme”.Now, Professor Johansen and her research group have created various stop molecules that prevent the “Judas enzyme” from sending the wrong messages to the cell nucleus. By doing so, the inflammatory reaction can be prevented. One of these stop molecules was recently tested in mice infected with psoriasis. The results are more than promising: Every single mouse got better, in all respects. In addition, it turned out that a high dosage yielded better effect than a low dosage.Medical testing right around the cornerThis discovery means that a substantial part of the road to a new type of medication is history. The next step is testing on humans. Early next year, the substance will be available as a cream, ready to be applied on the first test persons. This testing will take place in France.Professor Berit Johansen’s new firm, Avexxin, is also testing out two other molecules, one against rheumatoid arthritis, and one against nephritis.
By Hege Tunstad and Lisa Olstad/Gemini Research Journal
When the body thinks it is under attack, it defends itself in the best way possible, for instance by starting a defence inflammation.
This reaction is highly appropriate if the enemy is an influenza virus or something else that actually needs to be fought. However, sometimes the body misinterprets the signals, and starts a defence inflammation against a non-existent enemy. The result could be so-called autoimmune diseases: psoriasis, arthritis, Bechterew’s, asthma, allergies, ulcerative colitis, multiple sclerosis, Crohn’s disease – and numerous others. The list is longer than we care to imagine, and affects large parts of the population. “Judas enzyme” sends the wrong messageProfessor Berit Johansen at the Department of Biology at NTNU previously discovered which enzyme that misinterprets signals and reprograms cells to divide much faster than they should – thus provoking disease. The enzyme is called phospholipase A2, less formally known as the “Judas enzyme”.Now, Professor Johansen and her research group have created various stop molecules that prevent the “Judas enzyme” from sending the wrong messages to the cell nucleus. By doing so, the inflammatory reaction can be prevented. One of these stop molecules was recently tested in mice infected with psoriasis. The results are more than promising: Every single mouse got better, in all respects. In addition, it turned out that a high dosage yielded better effect than a low dosage.Medical testing right around the cornerThis discovery means that a substantial part of the road to a new type of medication is history. The next step is testing on humans. Early next year, the substance will be available as a cream, ready to be applied on the first test persons. This testing will take place in France.Professor Berit Johansen’s new firm, Avexxin, is also testing out two other molecules, one against rheumatoid arthritis, and one against nephritis.
By Hege Tunstad and Lisa Olstad/Gemini Research Journal
Wednesday, November 01, 2006
Psoriasis and Psoriatic Disorders
This study will evaluate a twice-daily topical treatment for body psoriasis in adolescents. Eligible patients must have body psoriasis, such as on arms, legs, chest, or back. The study involves six office visits (some visits require blood draws) with a board-certified dermatologist, and includes free treatment for up to eight weeks, and compensation for time and travel.
The research site is in Shreveport, La.
For more information
please see http://www.centerwatch.com/patient/studies/cat126.html.
The research site is in Shreveport, La.
For more information
please see http://www.centerwatch.com/patient/studies/cat126.html.
Tuesday, October 31, 2006
What Is Known About Psoriasis
Psoriasis is a chronic scaling skin. It may range from just a few spots anywhere on the body to large areas of involvement. It is not contagious or spread able from one part of the body to another or from one person to another.
There is no blood test to diagnose psoriasis. The diagnosis is made by observation and examination of the skin. Sometimes microscopic examination of the skin (biopsy) is helpful where the changes are not typical or characteristic.
The exact cause of psoriasis is unknown, but hereditary and genetic factors are important. Psoriasis runs in families. This does not mean, however, that every child of a parent with psoriasis will develop psoriasis, but it is common that somewhere down the line psoriasis will appear in families.
Psoriasis is not caused by allergies, infections, dietary deficiencies or excesses, or nervous tension.
There is no blood test to diagnose psoriasis. The diagnosis is made by observation and examination of the skin. Sometimes microscopic examination of the skin (biopsy) is helpful where the changes are not typical or characteristic.
The exact cause of psoriasis is unknown, but hereditary and genetic factors are important. Psoriasis runs in families. This does not mean, however, that every child of a parent with psoriasis will develop psoriasis, but it is common that somewhere down the line psoriasis will appear in families.
Psoriasis is not caused by allergies, infections, dietary deficiencies or excesses, or nervous tension.
Wednesday, October 18, 2006
Factors That May Influence Psoriasis
Most people living with psoriasis experience good days when their skin clears and bad days when psoriasis flares. A trigger is usually needed to make psoriasis appear — whether it is for the first time or the thirtieth. Common psoriasis triggers are:
Infection
Studies show that some infections can trigger psoriasis. Dermatologists have seen people with a family history of psoriasis get strep throat and develop their first psoriasis lesions two weeks later. Strep throat often precedes an outbreak of guttate psoriasis. Inverse psoriasis is frequently aggravated by a thrush infection. Infections that can trigger psoriasis are:
Candida albicans (thrush)
Human immunodeficiency virus (HIV)
Staphylococcal skin infections (boils)
Streptococcal pharyngitis (strep throat)
Viral upper respiratory condition
Treating the infection in many cases lessens or clears the psoriasis.
Reaction to Certain Medications
Some people develop psoriasis for the first time or experience a flare-up after taking certain medication. Medications that can trigger psoriasis are:
Anti-malarial drugs. Dermatologists have seen people develop psoriasis for the first time after taking an anti-malarial medication.
Beta-blockers (medication used to treat high blood pressure) and heart medication. These worsen psoriasis in some people.
Corticosteroids.
These medications, which range in potency from extremely mild to very strong, are used to treat psoriasis and can be very effective. It is important to use these medications as directed. Overuse and sudden withdrawal of some oral corticosteriods can aggravate psoriasis.
Indomethacin (non-steroidal medication used to treat arthritis and other inflammatory conditions) worsens psoriasis in some people.
Lithium (used to treat manic depression and other psychiatric conditions) aggravates psoriasis in about 50% of people who have psoriasis.
If you have psoriasis or a family history of psoriasis, be sure to let the doctor prescribing any of the above medications know. Other medications can sometimes be substituted.
Skin Injury
People with psoriasis often notice new lesions 10 to 14 days after the skin is cut, scratched, rubbed, or severely sunburned.
This is called the “Koebner phenomenon” and is named after Dr. Koebner who in the 19th century observed that a patient developed new lesions in areas where his horse bit him. This relationship between skin injury and developing new psoriatic lesions has been observed in many patients. Today, a wide range of traumas and skin conditions are known to trigger Koebner’s phenomenon:
Skin Trauma
Skin Conditions
Acupuncture
Boils
Bites
Dermatitis
Bruises
Herpes blisters
Burns
Lichen planus
Chafing
Scabies
Chemical irritation
Vitiligo
Cuts and scrapes
Other
Pressure against the skin
Shaving
Sunburn and peeling
Adhesive tape on the skin
Tattoos
Vaccinations
Other
Research shows that about 50% of people with psoriasis experience the Koebner phenomenon — developing a psoriatic lesion at the site of a skin injury or in the same place as another skin condition. About 10% of psoriasis patients develop a new psoriatic lesion each time the skin is injured. The likelihood of developing the Koebner phenomenon may increase when psoriasis lesions are already present.
Stress
Ask anyone with psoriasis what triggers a flare-up, and stress is likely to top the list. Scientific studies confirm that stress can worsen psoriasis and increase itching. Some people can even trace their first outbreak to a particularly stressful event.
Having psoriasis is, in itself, stressful. When lesions are visible, people may stare and not want to get near. They may ask, “What did you do to your skin?” Even a spouse, parents, children, friends, and co-workers can be visibly uncomfortable. Some people report that a spouse cannot bear to touch them during severe outbreaks. Others say they feel embarrassed or ashamed by their skin.
When psoriasis develops on the hands and feet, it is often difficult for people to perform daily tasks, such as picking up objects, typing, and walking. This can make holding a job or caring for a child extremely challenging. The itching and pain caused by psoriasis also makes daily life difficult.
Treating psoriasis can add to the stress. Some treatments are time-consuming. Broadband phototherapy requires three to five visits per week to a clinic, and narrowband requires two to three. Topical medications can be time-consuming to apply. After spending time and money to treat the psoriasis, a person may find the treatment ineffective. Potential side effects deter some people from opting for systemic medications, such as methotrexate and cyclosporine. The cost of treating psoriasis adds stress to many people’s lives. Some living with psoriasis find that they cannot afford to pay for the newer treatments, such as the biologics.
When the everyday stress of living with psoriasis is compounded by a stressful event at work, a personal crisis, or an especially hectic time, such as the holidays, the stress can feel overwhelming.
People may try to alleviate stress with an herbal or natural over-the-counter remedy. However, some food supplements and herbal remedies interact negatively with prescription medications. People also turn to alcohol and others drugs to reduce stress. Research shows that this actually increases stress.
Dermatologists recommend that their patients tell them if they feel overwhelming stress. There are many healthy ways to relieve stress. Many patients find that psychological counseling or joining a support group effectively reduces stress. Your dermatologist may be able to help you find a therapist or a support group. Some patients prefer to adopt a popular relaxation technique, such as meditation. Exercise also can help reduce stress.
Weather
Winter tends to be the most challenging season for people living with psoriasis. Numerous studies indicate cold weather is a common trigger for many people and that hot and sunny climates appear to clear the skin.
Cold winter weather is dry, and indoor heat robs the skin of needed moisture. This usually worsens psoriasis. Psoriasis can become even more severe when the stress of the holidays and winter illnesses combine to compromise immune systems.
While hot and sunny may help clear psoriasis, air-conditioning can dry out the skin and aggravate psoriasis. Moisturizing can help prevent this.
Other
Science has not uncovered all psoriasis triggers. Hormones, smoking, and heavy drinking appear to trigger psoriasis in some people.
How hormones affect psoriasis is still not well understood. Research shows that many people develop their first psoriatic lesions just after puberty when hormone levels fall. When hormones levels increase during pregnancy, psoriasis improves for many women. A recent study showed that 55% of pregnant women with psoriasis reported an improvement, 21% saw no change, and 23% experienced worsening. After delivery, only 9% reported improvement and 65% saw their psoriasis worsen. More research is needed to understand these effects.Research suggests that localized (on the palms and soles) pustular psoriasis may be more common in people who smoke tobacco. Other studies suggest a correlation between smoking and developing plaque psoriasis. There also seems to be a link between smoking and developing severe psoriasis. Quitting smoking improves psoriasis for some; however, quitting does not always clear the psoriasis. More research is needed in this area.It is now believed that heavy drinking may trigger psoriasis in some people. Heavy drinking also may make treatment less effective. Again, more research is needed.More Good Days than BadWhile there is no cure, psoriasis can be successfully managed so that one experiences more good days than bad. Numerous treatment options are available, and recent advances are revolutionizing the management and care of psoriasis. A dermatologist considers a patient’s overall health, age, lifestyle, and the severity of the psoriasis in order to find a treatment option that will achieve maximum effectiveness.
References:Behnam SM et al. “Smoking and psoriasis.” SKINmed. 2005 May-June;4(3):174-176.Bowcock AM et al.
“Genetics of psoriasis: The potential impact on new therapies.” Journal of the American Academy of Dermatology. 2003 August;49
(2):S51-55.Murase, JE et al. “Hormonal Effect on Psoriasis in Pregnancy and Post Partum.” Archives of Dermatology. 2005 May;141(5):601-606.
Infection
Studies show that some infections can trigger psoriasis. Dermatologists have seen people with a family history of psoriasis get strep throat and develop their first psoriasis lesions two weeks later. Strep throat often precedes an outbreak of guttate psoriasis. Inverse psoriasis is frequently aggravated by a thrush infection. Infections that can trigger psoriasis are:
Candida albicans (thrush)
Human immunodeficiency virus (HIV)
Staphylococcal skin infections (boils)
Streptococcal pharyngitis (strep throat)
Viral upper respiratory condition
Treating the infection in many cases lessens or clears the psoriasis.
Reaction to Certain Medications
Some people develop psoriasis for the first time or experience a flare-up after taking certain medication. Medications that can trigger psoriasis are:
Anti-malarial drugs. Dermatologists have seen people develop psoriasis for the first time after taking an anti-malarial medication.
Beta-blockers (medication used to treat high blood pressure) and heart medication. These worsen psoriasis in some people.
Corticosteroids.
These medications, which range in potency from extremely mild to very strong, are used to treat psoriasis and can be very effective. It is important to use these medications as directed. Overuse and sudden withdrawal of some oral corticosteriods can aggravate psoriasis.
Indomethacin (non-steroidal medication used to treat arthritis and other inflammatory conditions) worsens psoriasis in some people.
Lithium (used to treat manic depression and other psychiatric conditions) aggravates psoriasis in about 50% of people who have psoriasis.
If you have psoriasis or a family history of psoriasis, be sure to let the doctor prescribing any of the above medications know. Other medications can sometimes be substituted.
Skin Injury
People with psoriasis often notice new lesions 10 to 14 days after the skin is cut, scratched, rubbed, or severely sunburned.
This is called the “Koebner phenomenon” and is named after Dr. Koebner who in the 19th century observed that a patient developed new lesions in areas where his horse bit him. This relationship between skin injury and developing new psoriatic lesions has been observed in many patients. Today, a wide range of traumas and skin conditions are known to trigger Koebner’s phenomenon:
Skin Trauma
Skin Conditions
Acupuncture
Boils
Bites
Dermatitis
Bruises
Herpes blisters
Burns
Lichen planus
Chafing
Scabies
Chemical irritation
Vitiligo
Cuts and scrapes
Other
Pressure against the skin
Shaving
Sunburn and peeling
Adhesive tape on the skin
Tattoos
Vaccinations
Other
Research shows that about 50% of people with psoriasis experience the Koebner phenomenon — developing a psoriatic lesion at the site of a skin injury or in the same place as another skin condition. About 10% of psoriasis patients develop a new psoriatic lesion each time the skin is injured. The likelihood of developing the Koebner phenomenon may increase when psoriasis lesions are already present.
Stress
Ask anyone with psoriasis what triggers a flare-up, and stress is likely to top the list. Scientific studies confirm that stress can worsen psoriasis and increase itching. Some people can even trace their first outbreak to a particularly stressful event.
Having psoriasis is, in itself, stressful. When lesions are visible, people may stare and not want to get near. They may ask, “What did you do to your skin?” Even a spouse, parents, children, friends, and co-workers can be visibly uncomfortable. Some people report that a spouse cannot bear to touch them during severe outbreaks. Others say they feel embarrassed or ashamed by their skin.
When psoriasis develops on the hands and feet, it is often difficult for people to perform daily tasks, such as picking up objects, typing, and walking. This can make holding a job or caring for a child extremely challenging. The itching and pain caused by psoriasis also makes daily life difficult.
Treating psoriasis can add to the stress. Some treatments are time-consuming. Broadband phototherapy requires three to five visits per week to a clinic, and narrowband requires two to three. Topical medications can be time-consuming to apply. After spending time and money to treat the psoriasis, a person may find the treatment ineffective. Potential side effects deter some people from opting for systemic medications, such as methotrexate and cyclosporine. The cost of treating psoriasis adds stress to many people’s lives. Some living with psoriasis find that they cannot afford to pay for the newer treatments, such as the biologics.
When the everyday stress of living with psoriasis is compounded by a stressful event at work, a personal crisis, or an especially hectic time, such as the holidays, the stress can feel overwhelming.
People may try to alleviate stress with an herbal or natural over-the-counter remedy. However, some food supplements and herbal remedies interact negatively with prescription medications. People also turn to alcohol and others drugs to reduce stress. Research shows that this actually increases stress.
Dermatologists recommend that their patients tell them if they feel overwhelming stress. There are many healthy ways to relieve stress. Many patients find that psychological counseling or joining a support group effectively reduces stress. Your dermatologist may be able to help you find a therapist or a support group. Some patients prefer to adopt a popular relaxation technique, such as meditation. Exercise also can help reduce stress.
Weather
Winter tends to be the most challenging season for people living with psoriasis. Numerous studies indicate cold weather is a common trigger for many people and that hot and sunny climates appear to clear the skin.
Cold winter weather is dry, and indoor heat robs the skin of needed moisture. This usually worsens psoriasis. Psoriasis can become even more severe when the stress of the holidays and winter illnesses combine to compromise immune systems.
While hot and sunny may help clear psoriasis, air-conditioning can dry out the skin and aggravate psoriasis. Moisturizing can help prevent this.
Other
Science has not uncovered all psoriasis triggers. Hormones, smoking, and heavy drinking appear to trigger psoriasis in some people.
How hormones affect psoriasis is still not well understood. Research shows that many people develop their first psoriatic lesions just after puberty when hormone levels fall. When hormones levels increase during pregnancy, psoriasis improves for many women. A recent study showed that 55% of pregnant women with psoriasis reported an improvement, 21% saw no change, and 23% experienced worsening. After delivery, only 9% reported improvement and 65% saw their psoriasis worsen. More research is needed to understand these effects.Research suggests that localized (on the palms and soles) pustular psoriasis may be more common in people who smoke tobacco. Other studies suggest a correlation between smoking and developing plaque psoriasis. There also seems to be a link between smoking and developing severe psoriasis. Quitting smoking improves psoriasis for some; however, quitting does not always clear the psoriasis. More research is needed in this area.It is now believed that heavy drinking may trigger psoriasis in some people. Heavy drinking also may make treatment less effective. Again, more research is needed.More Good Days than BadWhile there is no cure, psoriasis can be successfully managed so that one experiences more good days than bad. Numerous treatment options are available, and recent advances are revolutionizing the management and care of psoriasis. A dermatologist considers a patient’s overall health, age, lifestyle, and the severity of the psoriasis in order to find a treatment option that will achieve maximum effectiveness.
References:Behnam SM et al. “Smoking and psoriasis.” SKINmed. 2005 May-June;4(3):174-176.Bowcock AM et al.
“Genetics of psoriasis: The potential impact on new therapies.” Journal of the American Academy of Dermatology. 2003 August;49
(2):S51-55.Murase, JE et al. “Hormonal Effect on Psoriasis in Pregnancy and Post Partum.” Archives of Dermatology. 2005 May;141(5):601-606.
Wednesday, October 11, 2006
Severe Psoriasis Linked to Heart Attacks
Severe forms of the itchy skin condition, psoriasis, should be considered a risk factor for heart attack, a new study suggests. Researchers who studied medical records for more than 680,000 British patients found that people in their 40s with severe psoriasis were more than twice as likely to suffer a heart attack than people without the skin disease.
The link may be inflammation, the body's normal response to injury and infection, which plays a role in both heart disease and psoriasis, researchers said.
Severe forms of the itchy skin condition, psoriasis, should be considered a risk factor for heart attack, a new study suggests. Researchers who studied medical records for more than 680,000 British patients found that people in their 40s with severe psoriasis were more than twice as likely to suffer a heart attack than people without the skin disease.
Mild psoriasis slightly raised the risk for heart attack, by 20 percent for people in their 40s. But study co-author Dr. Joel Gelfand of the University of Pennsylvania said people with mild psoriasis "on their elbows and knees" shouldn't worry.
"I don't want to overly alarm people," Gelfand said. "If you have psoriasis you should see a physician and go through a screening to make sure you don't have other cardiovascular risk factors."
The study, which was partly funded with a grant from the maker of a psoriasis drug, appears in Wednesday's Journal of the American Medical Association.
Psoriasis causes itchy, painful patches of thick, red, scaly skin. The chronic disease is thought to start with the immune system overreacting and targeting the body's own cells. More than 5 million Americans suffer from it, but most do not have the severest form.
There isn't a precise definition of severe psoriasis. About 100,000 Americans have 10 percent or more of their skin affected, and an estimated 500,000 say psoriasis is a significant problem for them in their everyday life.
People with psoriasis are more likely to smoke and to have diabetes, high blood pressure and high cholesterol. But the researchers found that even when they took those risk factors into account, psoriasis still increased the risk of heart attack.
Dr. Fred Leya of Loyola University Health System said cardiologists have long noticed the connection between psoriasis and heart disease. The study should encourage doctors to be more aggressive at controlling cardiovascular risk factors like cholesterol in their patients with psoriasis, he said.
"This is not a breakthrough discovery, but an important documentation of the facts," said Leya, who wasn't involved in the study.
Dr. William Weintraub, a cardiologist and research director at Christiana Care Health System in Newark, Del., questioned the study's importance for patients.
"Severe psoriasis is relatively uncommon, and the risk for heart attack with mild psoriasis is relatively minor," said Weintraub, who was not involved in the study.
Based on their findings, the researchers predict that 1 out of 623 people with severe psoriasis in their 40s will have a heart attack related to their psoriasis each year, Gelfand said. For mild cases, 1 in 3,646 people in their 40s would have a heart attack each year.
Gelfand and another co-author reported financial ties to companies investigating drug treatments for psoriasis. The study was funded by the National Institutes of Health and a grant to University of Pennsylvania from Cambridge, Mass.-based Biogen Idec Inc., which has a psoriasis drug in development.
The link may be inflammation, the body's normal response to injury and infection, which plays a role in both heart disease and psoriasis, researchers said.
Severe forms of the itchy skin condition, psoriasis, should be considered a risk factor for heart attack, a new study suggests. Researchers who studied medical records for more than 680,000 British patients found that people in their 40s with severe psoriasis were more than twice as likely to suffer a heart attack than people without the skin disease.
Mild psoriasis slightly raised the risk for heart attack, by 20 percent for people in their 40s. But study co-author Dr. Joel Gelfand of the University of Pennsylvania said people with mild psoriasis "on their elbows and knees" shouldn't worry.
"I don't want to overly alarm people," Gelfand said. "If you have psoriasis you should see a physician and go through a screening to make sure you don't have other cardiovascular risk factors."
The study, which was partly funded with a grant from the maker of a psoriasis drug, appears in Wednesday's Journal of the American Medical Association.
Psoriasis causes itchy, painful patches of thick, red, scaly skin. The chronic disease is thought to start with the immune system overreacting and targeting the body's own cells. More than 5 million Americans suffer from it, but most do not have the severest form.
There isn't a precise definition of severe psoriasis. About 100,000 Americans have 10 percent or more of their skin affected, and an estimated 500,000 say psoriasis is a significant problem for them in their everyday life.
People with psoriasis are more likely to smoke and to have diabetes, high blood pressure and high cholesterol. But the researchers found that even when they took those risk factors into account, psoriasis still increased the risk of heart attack.
Dr. Fred Leya of Loyola University Health System said cardiologists have long noticed the connection between psoriasis and heart disease. The study should encourage doctors to be more aggressive at controlling cardiovascular risk factors like cholesterol in their patients with psoriasis, he said.
"This is not a breakthrough discovery, but an important documentation of the facts," said Leya, who wasn't involved in the study.
Dr. William Weintraub, a cardiologist and research director at Christiana Care Health System in Newark, Del., questioned the study's importance for patients.
"Severe psoriasis is relatively uncommon, and the risk for heart attack with mild psoriasis is relatively minor," said Weintraub, who was not involved in the study.
Based on their findings, the researchers predict that 1 out of 623 people with severe psoriasis in their 40s will have a heart attack related to their psoriasis each year, Gelfand said. For mild cases, 1 in 3,646 people in their 40s would have a heart attack each year.
Gelfand and another co-author reported financial ties to companies investigating drug treatments for psoriasis. The study was funded by the National Institutes of Health and a grant to University of Pennsylvania from Cambridge, Mass.-based Biogen Idec Inc., which has a psoriasis drug in development.
Tuesday, September 26, 2006
Psoriasis Symptoms
Individuals with psoriasis experience skin conditions such as itching, cracking, stinging, burning, or bleeding (ICN Pharmaceuticals, Inc.). These symptoms are usually worse in the winter months due to the lack of sunlight and low indoor humidity (Hall 132). The skin is most likely to crack at the joints where the body bends or in areas where the individual fails to refrain from scratching. Scratching can also lead to bleeding and infection which is why it should be avoided at all costs. This skin condition has also been known to affect fingernails and toenails by causing pits or dents in them. There is also the possibility that the soft tissue inside the mouth and genitalia can be affected. In some cases, individuals experience joint inflammation, which can lead to the development of arthritis symptoms. This condition is known as psoriatic arthritis.
Friday, September 15, 2006
Psoriasis May Affect The Eyes
Psoriasis is a common skin disease. Ocular signs occur in approximately 10% of patients, and they are more common in men than in women. Patients with ocular findings almost always have psoriatic skin disease; however, it is rare for the eye to become involved before the skin.
Psoriasis involves hyperproliferation of the keratinocytes in the epidermis. The cause of the loss of control of keratinocyte turnover is unknown. However, environmental, genetic, and immunologic factors appear to play a role. Psoriasis is associated with certain human leukocyte antigen (HLA) alleles, particularly human leukocyte antigen Cw6 (HLA-Cw6). In some families, psoriasis is an autosomal dominant trait.
Disease exacerbations can be triggered by trauma, stress, alcohol, medications, and infection (eg, staphylococcal, streptococcal, human immunodeficiency virus). The epidermis is infiltrated by a large number of activated T cells, which appear to be capable of inducing keratinocyte proliferation. Conjunctival impression cytology demonstrated a higher incidence of squamous metaplasia, neutrophil clumping, and nuclear chromatin changes in patients with psoriasis.
Psoriasis involves hyperproliferation of the keratinocytes in the epidermis. The cause of the loss of control of keratinocyte turnover is unknown. However, environmental, genetic, and immunologic factors appear to play a role. Psoriasis is associated with certain human leukocyte antigen (HLA) alleles, particularly human leukocyte antigen Cw6 (HLA-Cw6). In some families, psoriasis is an autosomal dominant trait.
Disease exacerbations can be triggered by trauma, stress, alcohol, medications, and infection (eg, staphylococcal, streptococcal, human immunodeficiency virus). The epidermis is infiltrated by a large number of activated T cells, which appear to be capable of inducing keratinocyte proliferation. Conjunctival impression cytology demonstrated a higher incidence of squamous metaplasia, neutrophil clumping, and nuclear chromatin changes in patients with psoriasis.
Thursday, September 07, 2006
Statistics On Psoriasis
The following statistics show that psoriasis and psoriatic arthritis are common, life-altering and often debilitating conditions.
Worldwide
Psoriasis affects an estimated 2-3 percent of the world's population.
125 million people worldwide have psoriasis, according to the World Psoriasis Day consortium.
National health concern
According to the National Institutes of Health (NIH), between 5.8 and 7.5 million Americans have psoriasis.
Studies have shown that between 10 percent and 30 percent of people with psoriasis also develop psoriatic arthritis.
National Psoriasis Foundation Benchmark SurveyIn 2001, the National Psoriasis Foundation commissioned the Benchmark Survey on Psoriasis and Psoriatic Arthritis. The results provided prevalence information, increased our understanding of the impact of psoriasis and psoriatic arthritis, and demonstrated that psoriasis and psoriatic arthritis carry a substantial burden.
The statistics below come from the Benchmark Survey.
Prevalence
2.2 percent of American adults have been diagnosed with psoriasis, confirming that psoriasis is a common disease.
11 percent of those diagnosed with psoriasis have also been diagnosed with psoriatic arthritis. This is a prevalence of 0.25 percent of American adults in the general population.2
Psoriasis prevalence in African Americans was 1.3 percent compared to 2.5 percent of Caucasians.
Quality of life
Psoriasis is not a cosmetic problem. Nearly 60 percent reported their disease to be a large problem in their everyday life.
Nearly 40 percent with psoriatic arthritis reported their disease to be a large problem in everyday life.
Patients with psoriasis covering more of their body (more extensive skin disease) experienced a greater negative impact on their quality of life.
Psoriasis had a greater impact on quality of life in women and younger patients.
Treatment satisfaction
Less than 40 percent of respondents indicated they were very satisfied with any of the four therapies assessed in the study (acitretin [brand name Soriatane], cyclosporine, methotrexate or PUVA [psoralen plus ultraviolet light A]).
Nearly 80 percent of persons who were very dissatisfied with their treatment did not have severe disease (less than 10 palms of coverage or <10 percent BSA).
Members of the National Psoriasis Foundation reported their disease to be significantly less of a burden and were more satisfied with treatment.
Age of onset
Psoriasis often appears between the ages of 15 and 25, but can develop at any age.
Psoriatic arthritis usually develops between the ages of 30 and 50, but it can develop at any time.
Severity of psoriasis
The National Psoriasis Foundation defines mild psoriasis as affecting less than three percent of the body; 3 percent to 10 percent is considered moderate; more than ten percent is considered severe. The palm of the hand equals 1 percent of the skin. However, the severity of psoriasis is also measured by how psoriasis affects a person's quality of life. Psoriasis can have a serious impact even if it involves a small area, such as the palms of the hands or soles of the feet.
The majority of people with psoriasis have mild disease.
Nearly one-quarter of people with psoriasis have cases that are considered moderate to severe.
Cost of psoriasis
Overall costs of treating psoriasis may exceed $3 billion annually. A 1993 study estimated that between $2 and $3 billion was spent annually on psoriasis treatments.
Genetic aspects of psoriasis
About one out of three people with psoriasis report that a relative had psoriasis.
If one parent has psoriasis, a child has about a 10 percent chance of having psoriasis. If both parents have psoriasis, a child has approximately a 50 percent chance of developing the disease.
Worldwide
Psoriasis affects an estimated 2-3 percent of the world's population.
125 million people worldwide have psoriasis, according to the World Psoriasis Day consortium.
National health concern
According to the National Institutes of Health (NIH), between 5.8 and 7.5 million Americans have psoriasis.
Studies have shown that between 10 percent and 30 percent of people with psoriasis also develop psoriatic arthritis.
National Psoriasis Foundation Benchmark SurveyIn 2001, the National Psoriasis Foundation commissioned the Benchmark Survey on Psoriasis and Psoriatic Arthritis. The results provided prevalence information, increased our understanding of the impact of psoriasis and psoriatic arthritis, and demonstrated that psoriasis and psoriatic arthritis carry a substantial burden.
The statistics below come from the Benchmark Survey.
Prevalence
2.2 percent of American adults have been diagnosed with psoriasis, confirming that psoriasis is a common disease.
11 percent of those diagnosed with psoriasis have also been diagnosed with psoriatic arthritis. This is a prevalence of 0.25 percent of American adults in the general population.2
Psoriasis prevalence in African Americans was 1.3 percent compared to 2.5 percent of Caucasians.
Quality of life
Psoriasis is not a cosmetic problem. Nearly 60 percent reported their disease to be a large problem in their everyday life.
Nearly 40 percent with psoriatic arthritis reported their disease to be a large problem in everyday life.
Patients with psoriasis covering more of their body (more extensive skin disease) experienced a greater negative impact on their quality of life.
Psoriasis had a greater impact on quality of life in women and younger patients.
Treatment satisfaction
Less than 40 percent of respondents indicated they were very satisfied with any of the four therapies assessed in the study (acitretin [brand name Soriatane], cyclosporine, methotrexate or PUVA [psoralen plus ultraviolet light A]).
Nearly 80 percent of persons who were very dissatisfied with their treatment did not have severe disease (less than 10 palms of coverage or <10 percent BSA).
Members of the National Psoriasis Foundation reported their disease to be significantly less of a burden and were more satisfied with treatment.
Age of onset
Psoriasis often appears between the ages of 15 and 25, but can develop at any age.
Psoriatic arthritis usually develops between the ages of 30 and 50, but it can develop at any time.
Severity of psoriasis
The National Psoriasis Foundation defines mild psoriasis as affecting less than three percent of the body; 3 percent to 10 percent is considered moderate; more than ten percent is considered severe. The palm of the hand equals 1 percent of the skin. However, the severity of psoriasis is also measured by how psoriasis affects a person's quality of life. Psoriasis can have a serious impact even if it involves a small area, such as the palms of the hands or soles of the feet.
The majority of people with psoriasis have mild disease.
Nearly one-quarter of people with psoriasis have cases that are considered moderate to severe.
Cost of psoriasis
Overall costs of treating psoriasis may exceed $3 billion annually. A 1993 study estimated that between $2 and $3 billion was spent annually on psoriasis treatments.
Genetic aspects of psoriasis
About one out of three people with psoriasis report that a relative had psoriasis.
If one parent has psoriasis, a child has about a 10 percent chance of having psoriasis. If both parents have psoriasis, a child has approximately a 50 percent chance of developing the disease.
Tuesday, August 29, 2006
A Closer Look At Psoriasis
Psoriasis is a chronic scaling skin. It may range from just a few spots anywhere on the body to large areas of involvement. It is not contagious or spread able from one part of the body to another or from one person to another. There is no blood test to diagnose psoriasis. The diagnosis is made by observation and examination of the skin. Sometimes microscopic examination of the skin (biopsy) is helpful where the changes are not typical or characteristic. The exact cause of psoriasis is unknown, but hereditary and genetic factors are important. Psoriasis runs in families. This does not mean, however, that every child of a parent with psoriasis will develop psoriasis, but it is common that somewhere down the line psoriasis will appear in families. Psoriasis is not caused by allergies, infections, dietary deficiencies or excesses, or nervous tension.
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